The occipitofrontalis (also occipitofrontalis muscle, epicranius muscle, latin: musculus occipitofrontalis) is a facial muscle of the calvaria region consisting of paired occipital and frontal bellies, which are connected by the epicranial aponeurosis.

The occipitofrontalis muscle is very loosely bound to the bones but very firmly to the rest parts of the scalp. The occipitofrontalis consists of two bellies: the frontal belly and the occipital belly, which are connected by a tough flat epicranial aponeurosis, also known as the galea aponeurotica.

Both bellies of the occipitofrontalis are innervated by branches of the facial nerve (CN VII). The frontal belly is innervated by the temporal branch, while the occipital belly of the occipitofrontalis receives nerve supply from the posterior auricular nerve.

The occipitofrontalis is supplied with arterial blood by branches of the superficial temporal, ophthalmic, posterior auricular and occipital arteries.